Hello,
You are free to use 1-22 for TX/RX (transmit/receive). Unless you’re in a densely populated area of radio hobbyists, you may seldom if ever receive a response on those channels via simplex (handheld-to-handheld) simply due to limits of range. If you are hearing RX frequently on those channels, and still never get a response (for example roadwork, daycare, schools, etc) it’s likely because they have tones set on their radios to not hear unintended traffic.
If you can, I suggest grabbing an inexpensive radio to loan a buddy who will do simplex tests with you. Fun, of course, and really helpful to understand the behaviors of 462MHz propagation.
Additionally, see this link for the GMRS channel chart, specifying usage parameters:
https://wiki.radioreference.com/index.php/FRS/GMRS_combined_channel_chart
Have fun!