My opinion is go with the duplexer, its simpler solution. yes there will be loss, a well tuned Q circuit 6 cavity duplexer will be about 2.2 db ish loss at 450-470 mhz. Lets say a 7.4 db gain antenna - 2.2 db = 5.2 so still considerable antenna gain and higher the antenna the better. Its just UHF ....loss is inevitable..you just minimize it as much as reasonably possible.