You might be on the very edge of being able to talk simplex if you don't have too much between the locations. Worth trying. Might have to be outdoors to do it if there is a pretty clear line. I have been about to get 5 to 7 miles simplex in some locations. If the local repeater is not too far away and has some altitude for it's antenna that could work too. Everything depends on your local situation. I can reach a repeater from inside my house that is about 25 miles away, but it is also on top of a 5,000 foot mountain plus on a tower... and I am using a 771G whip antenna on my 5 watt HT.