Glad to hear you are having luck with the Stryker. Environmental conditions will play heavily into how well your radio can receive a weak signal. If you have a received signal that is only 1 S unit, but you have 3 S units of stray noise around you, you will never hear the 1 S unit signal. If you drive out of the high noise area, even if you get further away, the reduction is RF noise will allow you to have a conversation with that station, even at 1 S unit, and be able to have a 100% copy. As far as placement goes, as long as they are spaced in a way that one doesn't fall within a physical harmonic, you should be fine. It's damn near impossible to do on purpose. It's very unlikely that you will do it by mistake. I have noticed that when I key my GMRS while in high power, the noise level on my HF gear goes up. Nothing unreasonable, but when the squelch is open, I can notice it. That's all. When the squelch is closed, there is no impact. I have a 120 watt RMS amp on my 10m radio. Whenever I use the amp, I turn the GMRS gear off. Though, I have never actually experienced any of my HF gear causing issues with my VHF or UHF gear. That sounds like an awesome setup!