With GMRS, there are certain things that are consistent across the board.
It is a channelized service with a set of repeater channels.
The repeater channels use duplex(TX and RX on different frequencies). TX=transmit, RX=receive.
These frequencies are already programmed into a GMRS radio.
Most repeaters use tones to open up the squelch.
You must use the tone given (RX on the repeater, TX on your radio) otherwise the repeater will ignore you.
You do not have to use a tone for RX on your radio. Indeed, you should leave it out until you have everything else working.
Given this, look at your manual and programming software and see if it is starting to make sense.